Structure of palmitoylated BET3: insights into TRAPP complex assembly and membrane localization

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Structure of palmitoylated BET3: insights into TRAPP complex assembly and membrane localization.

BET3 is a component of TRAPP, a complex involved in the tethering of transport vesicles to the cis-Golgi membrane. The crystal structure of human BET3 has been determined to 1.55-A resolution. BET3 adopts an alpha/beta-plait fold and forms dimers in the crystal and in solution, which predetermines the architecture of TRAPP where subunits are present in equimolar stoichiometry. A hydrophobic poc...

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ژورنال

عنوان ژورنال: The EMBO Journal

سال: 2005

ISSN: 0261-4189,1460-2075

DOI: 10.1038/sj.emboj.7600565